product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
MRE11A / MRE11 Antibody (aa182-582, clone 4H9) LS-C53370
catalog :
LS-C53370
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4H9
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human
  • immunohistochemistry; human
Ollier M, Radosevic Robin N, Kwiatkowski F, Ponelle F, Viala S, Privat M, et al. DNA repair genes implicated in triple negative familial non-BRCA1/2 breast cancer predisposition. Am J Cancer Res. 2015;5:2113-26 pubmed
product information
AntibodyID :
53829
AntibodyName :
LS-C53370
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
MRE11A / MRE11 Antibody (aa182-582, clone 4H9) LS-C53370
Specificity :
human Mre11, an 80 kD protein that acts as a Mn+2- dependent double stranded DNA 3' to 5' exonuclease and a single stranded DNA endonuclease. It is part of a larger complex with Rad50, p95 (Nibrin), and possibly other proteins involved in the nucleolytic end-processing of double strand breaks and telomere maintenance
ClonalityDesc :
Monoclonal
CloneName :
4H9
AntibodyModification :
Unconjugated
AntigenModification :
aa182-582
PresentationDesc :
PBS, 0.01% Sodium Azide
ImmunogenType :
Fusion protein
ImmunogenDesc :
GST fusion protein corresponding to aa 182-582 of Mre11 expressed in E. coli.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
MRE11A / MRE11
StandardGeneSymbol :
MRE11A
Reactivity :
Human
Usage :
IHC, WB
ShortWebDescription :
MRE11 antibody LS-C53370 is an unconjugated mouse monoclonal antibody to human MRE11 (MRE11A) (aa182-582). Validated for IHC and WB. Cited in 1 publication.
Synonyms :
MRE11A, AT-like disease, Endo/exonuclease Mre11, HNGS1, MRE11, MRE11 homolog 1, MRE11 homolog A, MRE11B, ATLD
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.