This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
EMA / MUC1 Antibody (clone X19) LS-C52312
catalog :
LS-C52312
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
X19

The same clone is also sold as:
reactivity :
human
application :
immunocytochemistry
product information
AntibodyID :
52705
AntibodyName :
LS-C52312
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
EMA / MUC1 Antibody (clone X19) LS-C52312
Specificity :
VNTR5 and VNTR20 recombinant unglycosylated fragments of MUC1 protein and underglycosylated MUC1 prepared from tumor fluids or as a result of chemical treatment of human milk MUC1. These MAbs do not recognize natural MUC1 protein isolated from human milk by affinity purification on carbohydrate epitope specific MAbs and belong to MAb cluster 1-4 according to ISOMB TD-4 classification. No cross-reactivity with egg white avidin. MAbs M4H2, M2F1, M2C5, M2E104 and M3A106: Affinity >1 X 108 all MAbs. MAbs bind with high efficiency with different epitopes within the VNTR tandem repeat peptide region of MUC1 molecule, which have different conmations and peptide- carbohydrate compositions. MAb M4H2 reacts with VNTR20 recombinant unglycosylated fragment of MUC1 protein (and very weakly with monomeric MUC1 peptide), with deglycosylated and underglycosylated natural MUC1 (but not with completely glycosylated natural milk MUC1). MAbs M2F1, M2C5, M2E104, M3A106 efficiently recognize underglycosylated and natural MUC1 protein isolated from human milk by affinity chromatography. All these MAbs belong to MAb clusters 6 and 7 according to ISOMB TD-4 classification. Non cross-reactive with normal serum proteins and human tissues of non-epithelial origin.
ClonalityDesc :
Monoclonal
CloneName :
X19
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.4, 0.1% Sodium Azide
ImmunogenDesc :
High molecular weight (>300 kD) glycoprotein.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at 4°C. Avoid freezing.
IsotypeName :
IgG1
Gene :
EMA / MUC1
StandardGeneSymbol :
MUC1
gene family :
Mucin
Reactivity :
Human
Usage :
IF
ShortWebDescription :
MUC1 antibody LS-C52312 is an unconjugated mouse monoclonal antibody to human MUC1 (EMA). Validated for IF.
Synonyms :
MUC1, CA15-3, CD227, Carcinoma-associated mucin, CD227 antigen, DF3 antigen, Episialin, Epithelial membrane antigen, H23 antigen, H23AG, Krebs von den Lungen-6, MAM6, MUC1/ZD, MUC-1/SEC, Mucin-1, Pem, KL-6, MUC-1/X, Tumor-associated mucin, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, PUM, EMA, MUC-1, Mucin 1, transmembrane
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.