This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Rho Kinase / ROCK1 Antibody (aa1114-1126, clone 154C1465) LS-C511
catalog :
LS-C511
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
154C1465

The same clone is also sold as:
reactivity :
human
application :
western blot
product information
AntibodyID :
2733
AntibodyName :
LS-C511
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
Rho Kinase / ROCK1 Antibody (aa1114-1126, clone 154C1465) LS-C511
Specificity :
This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis.
ClonalityDesc :
Monoclonal
CloneName :
154C1465
AntibodyModification :
Unconjugated
AntigenModification :
aa1114-1126
PresentationDesc :
PBS, 0.05% Sodium Azide, 0.2% Gelatin
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to residues 1114-1126 GNLPESRIEGWLS of human ROCK-1. Immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Bovine, Dog, Bat, Horse, Opossum, Platypus (100%); Rabbit (92%); Chicken (85%).
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG
Gene :
Rho Kinase / ROCK1
StandardGeneSymbol :
ROCK1
gene family :
Protein Kinase
Subfamily :
ROCK
Reactivity :
Mouse, Dog, Bovine, Rat, Horse, Bat, Human, Monkey
Usage :
WB (1 - 2 µg/ml)
UsageNotRecommended :
IHC-P
ShortWebDescription :
ROCK1 antibody LS-C511 is an unconjugated mouse monoclonal antibody to ROCK1 (Rho Kinase) (aa1114-1126) from human. It is reactive with human, mouse, rat and other species. Validated for WB.
Synonyms :
ROCK1, p160 Rho-associated kinase, p160ROCK, p160 ROCK-1, p160-ROCK, p160RhoK, Rho-associated kinase, RockI, Rok, Rok alpha, Rho-alpha kinase, p160 rho-kinase, Rho kinase, ROCK-I, Rokalpha
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.