This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
RB1 / Retinoblastoma / RB Antibody (clone 172C1094) LS-C510
catalog :
LS-C510
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
172C1094

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry
product information
AntibodyID :
2732
AntibodyName :
LS-C510
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
RB1 / Retinoblastoma / RB Antibody (clone 172C1094) LS-C510
Specificity :
recognizes cleaved Rb (DRb-p70). Does not recognize full-length Rb. In camptothecin treated HL60, an ~68 kD band is observed. DRb-p70 exists in vivo as an N-terminally truncated form of Rb (Liu et al.). DRb-p70 is thought to be the product of alternative translation and is expressed in primary myeloid cells in fetal liver, bone marrow and spleen. DRb-p70 is also specifically expressed in tumor-associated macrophages (TAMs). TAMs are an important targets of cancer therapy. DRb-p70 is a marker of TAMs, and maybe useful for identifying tumors with macrophage infiltration (Liu et al, 2005).
ClonalityDesc :
Monoclonal
CloneName :
172C1094
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.02% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A synthetic peptide corresponding to a region of the caspase-3-induced cleavage site of human Rb.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: 4°C; Long term: -70°C.
IsotypeName :
IgG1
Gene :
RB1 / Retinoblastoma / RB
StandardGeneSymbol :
RB1
Reactivity :
Mouse, Human
Usage :
IHC, WB (2 µg/ml)
UsageNotRecommended :
IHC-P
ShortWebDescription :
RB antibody LS-C510 is an unconjugated mouse monoclonal antibody to RB (RB1 / Retinoblastoma) from human. It is reactive with human and mouse. Validated for IHC and WB.
Synonyms :
RB1, p105-Rb, Osteosarcoma, PRb, Retinoblastoma, Retinoblastoma 1, OSRC, RB, Pp110
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.