This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
PIM3 / PIM-3 Antibody LS-C501228
catalog :
LS-C501228
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
product information
AntibodyID :
514742
AntibodyName :
LS-C501228
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
PIM3 / PIM-3 Antibody LS-C501228
Specificity :
Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant Human Serine/threonine-protein kinase pim-3 protein (278-326AA)
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
IsotypeName :
IgG
Gene :
PIM3 / PIM-3
StandardGeneSymbol :
PIM3
gene family :
Protein Kinase
Subfamily :
PIM
Reactivity :
Mouse, Human
Usage :
ELISA, IF, IHC, WB
ShortWebDescription :
PIM-3 antibody LS-C501228 is an unconjugated rabbit polyclonal antibody to PIM-3 (PIM3) from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC and WB.
Synonyms :
PIM3, KID1, Pim-3 oncogene, Serine/threonine kinase Pim-3, Pim-3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.