This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
PECAM-1 / CD31 Antibody LS-C4888
catalog :
LS-C4888
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
5629
AntibodyName :
LS-C4888
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PECAM-1 / CD31 Antibody LS-C4888
Specificity :
Recognizes human. endothelial cells in normal tissues and in benign and malignant proliferations 100kD (endothelial cells) and 130kD (platelets). In cryostat sections and blood smears the antibody also stains megakaryocytes, platelets and occasionally plasma cells. It reacts weakly with mantle zone B cells, peripheral T cells, and neutrophils. Antibody to CD31 is of value in the study of benign and malignant vascular tumors. Staining for CD31 has also been used to measure angiogenesis, which reportedly predicts tumor recurrence. Species cross-reactivity: Does not react with rat or porcine.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% sodium azide, 40% glycerol.
ImmunogenType :
Membrane extract
ImmunogenDesc :
Membrane preparation of a spleen from a patient with hairy cell leukemia. Cellular Localization: Cell membrane.
PurificationDesc :
Tissue culture supernatant
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1,k
Gene :
PECAM-1 / CD31
StandardGeneSymbol :
PECAM1
Reactivity :
Human
Usage :
ELISA, IF, IHC, IHC-P (1:50)
ShortWebDescription :
CD31 antibody LS-C4888 is an unconjugated mouse monoclonal antibody to human CD31 (PECAM-1). Validated for ELISA, IF and IHC.
UsageText :
Suitable for use in ELISA, Immunofluorescence and Immunohistochemistry. Not suitable for Western Blot. Immunohistochemistry (Formalin/paraffin): 1:50 for 30min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 8.0 for 10-20 min., followed by cooling at RT for 20 min. Positive control: Placenta.
Synonyms :
PECAM1, CD31, CD31 antigen, EndoCAM, PECA1, PECAM-1, GPIIA
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.