product summary
Loading...
company name :
LifeSpan Biosciences
product type :
antibody
product name :
HLA-E Antibody (clone MEM-E/08) LS-C46065
catalog :
LS-C46065
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MEM-E/08
reactivity :
human
application :
immunoprecipitation, flow cytometry
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Merino A, Sabbaj S, Easlick J, Goepfert P, Kaslow R, Tang J. Dimorphic HLA-B signal peptides differentially influence HLA-E- and natural killer cell-mediated cytolysis of HIV-1-infected target cells. Clin Exp Immunol. 2013;174:414-23 pubmed publisher
product information
AntibodyID :
45881
AntibodyName :
LS-C46065
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
HLA-E Antibody (clone MEM-E/08) LS-C46065
Specificity :
The antibody MEM-E/08 recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results revealed that antibody is remarkably specific for HLA-E, only with weak cross-reactivity with following classical MHC Class I molecules (MHC Class Ia): HLA-A24, -B7, -B27, -B51, -B54, -C7.
ClonalityDesc :
Monoclonal
CloneName :
MEM-E/08
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.4, 15 mM Sodium Azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide
PurificationDesc :
Purified by protein-A affinity chromatography. Greater than 95% by SDS-PAGE.
RecommendedStorageDesc :
Store at 2°C to 8°C. Do not freeze.
IsotypeName :
IgG1
Gene :
HLA-E
StandardGeneSymbol :
HLA-E
Reactivity :
Human
Usage :
Flo, IP
UsageNotRecommended :
IHC-P
ShortWebDescription :
HLA-E antibody LS-C46065 is an unconjugated mouse monoclonal antibody to human HLA-E. Validated for Flow and IP.
Synonyms :
HLA-E, EA2.1, HLAE, MHC HLA-E alpha-2.1, MHC HLA-E alpha-1, EA1.2, HLA-6.2, MHC class I antigen E, QA1
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.