This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
ITGA6/Integrin Alpha 6/CD49f Antibody (clone NKI-GoH3, RPE) LS-C45281
catalog :
LS-C45281
clonality :
monoclonal
host :
rat
conjugate :
RPE
clone name :
NKI-GoH3

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
product information
AntibodyID :
45019
AntibodyName :
LS-C45281
TargetSpecies :
Human
Host Species :
Rat
Product Name :
ITGA6/Integrin Alpha 6/CD49f Antibody (clone NKI-GoH3, RPE) LS-C45281
Specificity :
Recognizes CD49F (VLA-6 alpha chain), a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Clone Reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukemia cells (alpha-6 beta-1). In immunohistology the monoclonal Reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin. XXX recommend the use of MCA699XZ for this purpose.
ClonalityDesc :
Monoclonal
CloneName :
NKI-GoH3
AntibodyModification :
RPE
PresentationDesc :
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
ImmunogenType :
Cells
ImmunogenDesc :
BALB/c mouse mammary tumor cells
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
ResuspensionLiquidDesc :
Reconstitute with distilled water.
IsotypeName :
IgG2a
Gene :
ITGA6/Integrin Alpha 6/CD49f
StandardGeneSymbol :
ITGA6
gene family :
Integrin
Reactivity :
Human
Usage :
Flo (1:1 - 1:5)
ShortWebDescription :
CD49f antibody LS-C45281 is an RPE-conjugated rat monoclonal antibody to human CD49f (ITGA6 / Integrin Alpha 6). Validated for Flow.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 platelets in 100 ul. Method sheets are available on request.
Synonyms :
ITGA6, CD49f, CD49f antigen, Integrin alpha6B, Integrin, alpha 6, Integrin alpha-6 precursor, VLA-6, Integrin alpha-6, ITGA6B
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.