This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
ITGAM / CD11b Antibody (clone ED7) LS-C45257
catalog :
LS-C45257
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human, rat
application :
immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
44995
AntibodyName :
LS-C45257
TargetSpecies :
Rat
Host Species :
Mouse
Product Name :
ITGAM / CD11b Antibody (clone ED7) LS-C45257
Specificity :
Recognizes a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes. Like ED8, Recognizes small ramified microglia in the central nervous system. No other cell types are positive for ED7, except for the cilia of the bronchus epithelium. The recognized antigen is a heterodimer (160 and 95kD) belonging to the family of adhesion molecules (CD11b/CD18). ED7 and ED8 may recognize closely related epitopes on the same molecule. ED7 and ED8 have been shown to induce homotypic aggregation of granulocytes.
ClonalityDesc :
Monoclonal
CloneName :
ED7
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenDesc :
Rat spleen cell homogenate.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
ResuspensionLiquidDesc :
Reconstitute in deionized water
IsotypeName :
IgG1
Gene :
ITGAM / CD11b
StandardGeneSymbol :
ITGAM
gene family :
Integrin
Reactivity :
Rat
Usage :
Flo, IHC, IHC-Fr (1:500)
ShortWebDescription :
CD11b antibody LS-C45257 is an unconjugated mouse monoclonal antibody to rat CD11b (ITGAM). Validated for Flow and IHC.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul.
Synonyms :
ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.
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