product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IL6R / IL6 Receptor Antibody (clone B-R6) LS-C45194
catalog :
LS-C45194
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-R6
reactivity :
human
application :
ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; human
Suttle M, Nilsson G, Snellman E, Harvima I. Experimentally induced psoriatic lesion associates with interleukin (IL)-6 in mast cells and appearance of dermal cells expressing IL-33 and IL-6 receptor. Clin Exp Immunol. 2012;169:311-9 pubmed publisher
product information
AntibodyID :
44932
AntibodyName :
LS-C45194
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IL6R / IL6 Receptor Antibody (clone B-R6) LS-C45194
Specificity :
Recognizes soluble and membranous human IL-6R. Has been shown to inhibit IL-6 mediated proliferation of XG-1 cells, and partially blocks binding of IL-6 to its receptor.
ClonalityDesc :
Monoclonal
CloneName :
B-R6
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenDesc :
CHO cells transfected with cDNA of the IL-6 receptor.
PurificationDesc :
Ion exchange chromatography
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
IL6R / IL6 Receptor
StandardGeneSymbol :
IL6R
gene family :
Interleukin
Reactivity :
Human
Usage :
ELISA, Flo (1:50), IF, IHC, IHC-Fr, IP
ShortWebDescription :
IL6 Receptor antibody LS-C45194 is an unconjugated mouse monoclonal antibody to human IL6 Receptor (IL6R). Validated for ELISA, Flow, IF, IHC and IP.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul.Removal of Sodium azide is recommended prior to use in functional assays.
Synonyms :
IL6R, CD126, gp80, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6Q, IL-6 receptor subunit alpha, IL-6R 1, IL-6R-1, Interleukin 6 receptor, Membrane glycoprotein 80, CD126 antigen, IL6RA, IL6RQ
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.