This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
SIGLEC1 / CD169 / Sialoadhesin Antibody (clone ED3) LS-C45080
catalog :
LS-C45080
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
ED3

The same clone is also sold as:
reactivity :
human, rat
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
44818
AntibodyName :
LS-C45080
TargetSpecies :
Rat
Host Species :
Mouse
Product Name :
SIGLEC1 / CD169 / Sialoadhesin Antibody (clone ED3) LS-C45080
Specificity :
Recognizes the rat CD169 cell surface antigen, a 185kD molecule expressed by macrophages, predominately confined to lymphoid organs only. Monocytes and granulocytes are negative. No other cell types are positive. The most conspicuous property of ED3 is it stains marginal zone macrophages and marginal metallophils in the spleen very strongly. Furthermore, macrophages in (auto-immune) diseased tissues express the ED3 antigen. In healthy tissue no expression occurs. CD169 is a receptor for glycoconjugates containing sialic acid.
ClonalityDesc :
Monoclonal
CloneName :
ED3
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenDesc :
Rat spleen cell homogenate.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG2a
Gene :
SIGLEC1 / CD169 / Sialoadhesin
StandardGeneSymbol :
SIGLEC1
gene family :
Immunoglobulin
Reactivity :
Rat
Usage :
Flo (1:500), IF, IHC, IHC-Fr (1:250), IP
ShortWebDescription :
Sialoadhesin antibody LS-C45080 is an unconjugated mouse monoclonal antibody to rat Sialoadhesin (SIGLEC1 / CD169). Validated for Flow, IF, IHC and IP.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Synonyms :
SIGLEC1, CD169, CD169 antigen, SIGLEC-1, Sialoadhesin, SN, DJ1009E24.1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.