This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
ITGAM / CD11b Antibody (clone OX-42, Biotin) LS-C45058
catalog :
LS-C45058
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
OX-42

The same clone is also sold as:
reactivity :
human, rat
application :
immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
44796
AntibodyName :
LS-C45058
TargetSpecies :
Rat
Host Species :
Mouse
Product Name :
ITGAM / CD11b Antibody (clone OX-42, Biotin) LS-C45058
Specificity :
Recognizes the rat equivalent of human CD11b, the receptor for the iC3b component of complement. The antigen is expressed on most macrophages, including resident and activated peritoneal macrophages and Kupffer cells and around 35% of alveolar macrophages. The antibody also labels dendritic cells, granulocytes and microglial cells in the brain. Clone MRC OX-42 has been reported as being suitable for use on paraffin-embedded material following PLP fixation (periodate-lysine-paraformaldehyde). Functionally, clone OX-42 inhibits complement mediated rosettes(1). XXX recommend the use of MCA275EL for use in functional studies.
ClonalityDesc :
Monoclonal
CloneName :
OX-42
AntibodyModification :
Biotin
PresentationDesc :
PBS, 0.09% Sodium Azide, 1% BSA
ImmunogenType :
Cells
ImmunogenDesc :
Rat peritoneal macrophages
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG2a
Gene :
ITGAM / CD11b
StandardGeneSymbol :
ITGAM
gene family :
Integrin
Reactivity :
Rat
Usage :
Flo (1:1 - 1:10), IHC, IHC-Fr
ShortWebDescription :
CD11b antibody LS-C45058 is a biotin-conjugated mouse monoclonal antibody to rat CD11b (ITGAM). Validated for Flow and IHC.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Synonyms :
ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.