This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
ANXA5 / Annexin V Antibody (clone VAA-33, FITC) LS-C45040
catalog :
LS-C45040
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
VAA-33

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
product information
AntibodyID :
44778
AntibodyName :
LS-C45040
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
ANXA5 / Annexin V Antibody (clone VAA-33, FITC) LS-C45040
Specificity :
Recognizes human Annexin V, a phospholipid binding protein which binds with high affinity and selectivity to phosphatidylserine (PS), in the presence of calcium. The translocation of PS from the cytosolic leaflet to the outer leaflet of the plasma membrane, due to a loss in plasma membrane asymmetry during apoptosis, acts as an in vivo signal for the removal of the dying cell by phagocytosis. Detection of PS using Annexin V therefore provides a reliable diagnostic tool for the indication of early programmed cell death. Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin V, are associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc). Clone VAA-33 may be used for intracellular staining following cell permeabilization ( BUF09).
ClonalityDesc :
Monoclonal
CloneName :
VAA-33
AntibodyModification :
FITC
PresentationDesc :
TBS, 0.02% Sodium Azide, 1% BSA
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant Annexin V.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG2a
Gene :
ANXA5 / Annexin V
StandardGeneSymbol :
ANXA5
Reactivity :
Human
Usage :
Flo
ShortWebDescription :
Annexin V antibody LS-C45040 is an FITC-conjugated mouse monoclonal antibody to human Annexin V (ANXA5). Validated for Flow.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Method sheets are available on request.
Synonyms :
ANXA5, ANX5, Anchorin CII, Calphobindin I, CBP-I, ENX2, PP4, RPRGL3, Lipocortin V, Thromboplastin inhibitor, VAC-alpha, Vascular anticoagulant-alpha, PAP-I, Annexin A5, Annexin V, Annexin-5, Endonexin II
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.