This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
XRCC5 / Ku80 Antibody LS-C45036
catalog :
LS-C45036
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
immunoprecipitation
product information
AntibodyID :
44774
AntibodyName :
LS-C45036
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
XRCC5 / Ku80 Antibody LS-C45036
Specificity :
Recognizes the 80kD subunit of human Ku protein, an evolutionarily conserved nuclear ATP-dependent DNA helicase, involved in a major proportion of DNA repair and in V(D)J recombination. The Ku protein, originally described as an autoantigen, exists as a tightly associated heterodimer consisting of a 70kD (Ku70) and 80kD (Ku80) subunit which binds to DNA double-strand break ends (DSB). DNA bound Ku recruits the large catalytic subunit DNA-PKcs to form the DNA-dependent protein kinase complex DNA-PK, facilitating DNA repair by the non-homologous end-joining (NHEJ) pathway. Is reported as suitable for use in immunocytochemistry.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.4, 0.09% Sodium Azide
ImmunogenType :
Cells
ImmunogenDesc :
Human T lymphocytes
PurificationDesc :
Protein A purified
IsotypeName :
IgG2a
Gene :
XRCC5 / Ku80
StandardGeneSymbol :
XRCC5
Reactivity :
Human
Usage :
IP
ShortWebDescription :
Ku80 antibody LS-C45036 is an unconjugated mouse monoclonal antibody to human Ku80 (XRCC5 ). Validated for IP.
Synonyms :
XRCC5, 86 kDa subunit of Ku antigen, CTC85, CTCBF, DNA repair protein XRCC5, G22P2, KARP-1, Ku autoantigen, 80kDa, NFIV, KARP1, Ku86, KUB2, TLAA, Nuclear factor IV, KU80, Thyroid-lupus autoantigen
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.