This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IRF5 Antibody (aa176-240, clone 10T1) LS-C45031
catalog :
LS-C45031
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10T1

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunoprecipitation, immunohistochemistry - paraffin section
product information
AntibodyID :
44769
AntibodyName :
LS-C45031
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IRF5 Antibody (aa176-240, clone 10T1) LS-C45031
Specificity :
Recognizes human interferon regulatory factor 5 (IRF5), a 58kD member of the IRF family which acts as a key regulator of interferon gene transcription, and is expressed in B cells and dendritic cells, and is inducible by type I interferon (IFN) in most lymphoid cells. The role of IRF3 and IRF7 as transcriptional mediators of virus- and IFN-induced signaling pathways is well documented. Studies have shown that IRF5 can also regulate IFN gene transcription, but appears to be more restricted in its cellular expression and range of viral stimuli, and has the ability to induce a wide range of chemokines involved in T-lymphocyte recruitment, including RANTES, MCP-1 and IP-10.
ClonalityDesc :
Monoclonal
CloneName :
10T1
AntibodyModification :
Unconjugated
AntigenModification :
aa176-240
PresentationDesc :
PBS, 0.1% Sodium Azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human IRF5 (176-240aa) purified from E. coli.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
IRF5
StandardGeneSymbol :
IRF5
Reactivity :
Human
Usage :
ELISA, IHC-P, IP, WB (1:1000 - 1:2000)
ShortWebDescription :
IRF5 antibody LS-C45031 is an unconjugated mouse monoclonal antibody to human IRF5 (aa176-240). Validated for ELISA, IHC, IP and WB.
UsageText :
Western Blot: LS-C45031 detects a band of approximately 58kD in THP-1 cell lysates.
Synonyms :
IRF5, Interferon regulatory factor 5, IRF-5, SLEB10, IBD14
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.