This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IRF3 Antibody (aa108-166, clone 3F10) LS-C45030
catalog :
LS-C45030
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3F10

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunoprecipitation
product information
AntibodyID :
44768
AntibodyName :
LS-C45030
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IRF3 Antibody (aa108-166, clone 3F10) LS-C45030
Specificity :
Recognizes human interferon regulatory factor 3 (IRF3), a 55kD constitutively expressed member of the IRF family, which acts as vital regulator of gene expression in innate immunity. IRF3 accumulates in an inactive form in the cytoplasm and then translocates to the nucleus as a homodimer, following stimuli-induced phosphorylation of specific serine/threonine residues. Association of the homodimer with p300/CBP (CREBB binding protein) forms dsRNA-activated factor 1 (DRAF1), which then activates the transcription of interferon alpha and beta, along with other interferon-induced genes.
ClonalityDesc :
Monoclonal
CloneName :
3F10
AntibodyModification :
Unconjugated
AntigenModification :
aa108-166
PresentationDesc :
PBS, 0.01% Sodium Azide, 10% Glycerol
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human IRF3 (108-166aa) purified from E. coli.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
IRF3
StandardGeneSymbol :
IRF3
Reactivity :
Human
Usage :
ELISA, IP, WB (1:2000 - 1:3000)
ShortWebDescription :
IRF3 antibody LS-C45030 is an unconjugated mouse monoclonal antibody to human IRF3 (aa108-166). Validated for ELISA, IP and WB.
UsageText :
Western Blot: LS-C45030 detects a band of approximately 55kD in HeLa cell lysates.
Synonyms :
IRF3, Interferon regulatory factor 3, IRF-3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.