This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Complement C4d Antibody (clone 057-51.5.1.6) LS-C44998
catalog :
LS-C44998
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
057-51.5.1.6

The same clone is also sold as:
reactivity :
human
application :
flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
44736
AntibodyName :
LS-C44998
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
Complement C4d Antibody (clone 057-51.5.1.6) LS-C44998
Specificity :
Recognizes a neoantigen on the secreted protein complement component 4d (C4d). The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4b's alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonization and activation of the classical pathway. This requires C4 binding protein or CR1 as a cofactor. iC4b is further degraded into C4d and C4c. The short half life of C4d means that it is present in serum at high enough concentrations to make it a useful marker for classical complement activation. C4 has been linked to susceptibility to systemic lupus erythematosus.
ClonalityDesc :
Monoclonal
CloneName :
057-51.5.1.6
AntibodyModification :
Unconjugated
PresentationDesc :
BBS, 0.1% Sodium Azide
ImmunogenDesc :
Purified human C4d.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
Complement C4d
Reactivity :
Human
Usage :
ELISA, Flo, IHC-Fr
ShortWebDescription :
Complement C4d antibody LS-C44998 is an unconjugated mouse monoclonal antibody to human Complement C4d. Validated for ELISA, Flow and IHC.
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.