This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Complement C3 Antibody (clone 053A-514.3.1.4) LS-C44997
catalog :
LS-C44997
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
053A-514.3.1.4

The same clone is also sold as:
reactivity :
human
application :
immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
44735
AntibodyName :
LS-C44997
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
Complement C3 Antibody (clone 053A-514.3.1.4) LS-C44997
Specificity :
Specific for human complement component 3d (C3d) neoantigen, a 33kD polypeptide fragment generated over the course of complement activation in which where complement 3 (C3) convertases cleave C3 to C3b, which is further degraded into iC3b and C3dg/C3d. C3d is involved in the regulation of many aspects of the immune response, including antigen processing and presentation. The C3d/antigen complex mediates B cell activation by simultaneously binding antigen-specific surface bound immunoglobulin and CD21, lowering the complement activation threshold. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.
ClonalityDesc :
Monoclonal
CloneName :
053A-514.3.1.4
AntibodyModification :
Unconjugated
PresentationDesc :
BBS, 0.1% Sodium Azide
ImmunogenDesc :
Purified human C3d (neoantigen).
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
Complement C3
StandardGeneSymbol :
C3
Reactivity :
Human
Usage :
ELISA, Flo, IHC, IHC-Fr
ShortWebDescription :
Complement C3 antibody LS-C44997 is an unconjugated mouse monoclonal antibody to human Complement C3. Validated for ELISA, Flow and IHC.
Synonyms :
C3, AHUS5, ARMD9, Complement component C3, CPAMD1, Complement C3, ASP, Complement component 3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.