This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CFB / Complement Factor B Antibody (N-Terminus, clone 014III-33.2.4.3) LS-C44996
catalog :
LS-C44996
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
014III-33.2.4.3

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
44734
AntibodyName :
LS-C44996
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
CFB / Complement Factor B Antibody (N-Terminus, clone 014III-33.2.4.3) LS-C44996
Specificity :
Recognizes the 30kD Ba fragment of 90kD human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit), leaving the 63 kD Bb subunit associated with C3b, forming C3 convertase. Subunit Ba inhibits lymphocyte proliferation. Conversely, subunit Bb is involved in the proliferation of preactivated B lymphocytes. Binds both the Ba fragment and the whole protein so is not suitable for all ELISA applications.
ClonalityDesc :
Monoclonal
CloneName :
014III-33.2.4.3
AntibodyModification :
Unconjugated
AntigenModification :
N-Terminus
PresentationDesc :
BBS, 0.1% Sodium Azide
ImmunogenDesc :
Purified human complement factor b.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
CFB / Complement Factor B
StandardGeneSymbol :
CFB
gene family :
Protease
Subfamily :
Serine S1
Reactivity :
Human
Usage :
ELISA, Flo, IHC, IHC-Fr, WB
ShortWebDescription :
Complement Factor B antibody LS-C44996 is an unconjugated mouse monoclonal antibody to human Complement Factor B (CFB) (N-Terminus). Validated for ELISA, Flow, IHC and WB.
UsageText :
ELISA: LS-C44996 binds both the Ba fragment and the whole protein so is not suitable for all ELISA applications.
Synonyms :
CFB, AHUS4, B-factor, properdin, C3/C5 convertase, CFAB, C3 proaccelerator, C3 proactivator, Complement factor B, Complement protein Factor B, Glycine-rich beta-glycoprotein, GBG, Factor B, FB, Glycine-rich beta glycoprotein, PBF2, BF, BFD, FBI12, H2-Bf, Properdin factor B
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.