This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Complement C8 Antibody (clone 056B-373) LS-C44994
catalog :
LS-C44994
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
056B-373

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
44732
AntibodyName :
LS-C44994
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
Complement C8 Antibody (clone 056B-373) LS-C44994
Specificity :
Recognizes complement component 8 (C8), a 151 kD member of the complement C6/C7/C8/C9 family, present in blood serum. C8 is a terminal component of the complement system, part of both the complement membrane attack complex (MAC), and important to MAC assembly. C8 binds to the C5b-7 complex, anchored to the membrane, creating C5b-8. C5b-8 binds C9 and catalyses the polymerization of C9 molecules to form C5-b9 (MAC). C8 is thought to contain lipid binding sites, facilitating the insertion of MAC into the membrane. Defects in the alpha chain of C8 can result in complement C8 deficiency type I. Furthermore, C8 deficiencies can cause recurring bacterial infections, in particular from Neisseria meningitides.
ClonalityDesc :
Monoclonal
CloneName :
056B-373
AntibodyModification :
Unconjugated
PresentationDesc :
BBS, 0.1% Sodium Azide
ImmunogenDesc :
Purified human C8.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
Complement C8
Reactivity :
Human
Usage :
ELISA, Flo, IHC, IHC-Fr, WB
ShortWebDescription :
Complement C8 antibody LS-C44994 is an unconjugated mouse monoclonal antibody to human Complement C8. Validated for ELISA, Flow, IHC and WB.
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.