This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
TNFRSF4 / CD134 / OX40 Antibody (clone 7D6) LS-C44970
catalog :
LS-C44970
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
reactivity :
human
application :
western blot, flow cytometry
product information
AntibodyID :
44708
AntibodyName :
LS-C44970
TargetSpecies :
Cat
Host Species :
Mouse
Product Name :
TNFRSF4 / CD134 / OX40 Antibody (clone 7D6) LS-C44970
Specificity :
Recognizes feline CD134, otherwise known as OX40, a 43kD type I membrane protein and member of the tumor necrosis factor receptor superfamily, expressed predominantly by CD4+ activated T cells, and a key regulator of T cell-dependent immune responses. CD134 has been identified as the receptor for the OX40 ligand, CD252, expressed by activated B cells, acting as a co-stimulatory signal for the stimulation and secretion of immunoglobulins. CD134 has also been identified as a binding receptor for Feline Immunodeficiency Virus (FIV), acting along with CXC chemokine receptor 4 (CXCR4) to facilitate the entry of the virus into CD4+ primary target cells.
ClonalityDesc :
Monoclonal
CloneName :
7D6
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Fusion protein
ImmunogenDesc :
CHO-derived feline CD134-Fc fusion protein.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
TNFRSF4 / CD134 / OX40
StandardGeneSymbol :
TNFRSF4
gene family :
TNF Receptor
Reactivity :
Cat
NonReactiveSpecies :
Mouse
Usage :
Flo, WB (1 µg/ml)
ShortWebDescription :
OX40 antibody LS-C44970 is an unconjugated mouse monoclonal antibody to cat OX40 (TNFRSF4 / CD134). Validated for Flow and WB.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Method sheets are available on request. Western Blot: LS-C44970 detects a band of approximately 43kD.
Synonyms :
TNFRSF4, ACT35 antigen, ATC35 antigen, CD134, ACT35, OX40, OX40 antigen, OX40L receptor, OX40 homologue, CD134 antigen, OX40 cell surface antigen, TXGP1L
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.
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