CD79A / CD79 Alpha Antibody (Cytoplasmic Domain, clone HM57, FITC) LS-C44953 | LifeSpan Biosciences LS-C44953 product information

product summary

company name :

LifeSpan Biosciences

product type :

antibody

product name :

CD79A / CD79 Alpha Antibody (Cytoplasmic Domain, clone HM57, FITC) LS-C44953

catalog :

LS-C44953

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

HM57

reactivity :

human, mouse

application :

western blot, flow cytometry

more info or order :

LifeSpan Biosciences product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; mouse	Verma Gaur J, Hauser J, Grundström T. Negative feedback regulation of antigen receptors through calmodulin inhibition of E2A. J Immunol. 2012;188:6175-83 pubmed publisher
	Hauser J, Verma Gaur J, Grundström T. Broad feedback inhibition of pre-B-cell receptor signaling components. Mol Immunol. 2013;54:247-53 pubmed publisher

product information

AntibodyID :

44691

AntibodyName :

LS-C44953

TargetSpecies :

Human

Host Species :

Mouse

Product Name :

CD79A / CD79 Alpha Antibody (Cytoplasmic Domain, clone HM57, FITC) LS-C44953

Specificity :

Recognizes an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells. The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin

ClonalityDesc :

Monoclonal

CloneName :

HM57

AntibodyModification :

FITC

AntigenModification :

Cytoplasmic Domain

PresentationDesc :

PBS, 0.09% Sodium Azide, 1% BSA

ImmunogenType :

Synthetic peptide

ImmunogenDesc :

Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1

PurificationDesc :

Protein G purified

RecommendedStorageDesc :

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.

IsotypeName :

IgG1

Gene :

CD79A / CD79 Alpha

StandardGeneSymbol :

CD79A

Reactivity :

Human

Usage :

Flo (1:1 - 1:5)

ShortWebDescription :

CD79 Alpha antibody LS-C44953 is an FITC-conjugated mouse monoclonal antibody to human CD79 Alpha (CD79A) (Cytoplasmic Domain). Validated for Flow. Cited in 2 publications.

UsageText :

Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Membrane permeabilization is required for this application. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Synonyms :

CD79A, CD79a antigen, Ig-alpha, MB-1, MB-1 membrane glycoprotein, Surface IgM-associated protein, MB1

SalesRegion :

Worldwide

more info or order :

LifeSpan Biosciences product webpage

company information

LifeSpan Biosciences

2401 Fourth Avenue, Suite 900
Seattle, WA 98121

CustomerSupport@lsbio.com

https://www.lsbio.com

1-206-464-1554

headquarters: USA

Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.