This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
RBP / Retinol Binding Protein Antibody (C-Terminus) LS-C44949
catalog :
LS-C44949
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; rat
Yamana D, Shimizu T, Fan Y, Miura T, Nanashima N, Yamada T, et al. Decrease of hepatic stellate cells in rats with enhanced sensitivity to clofibrate-induced hepatocarcinogenesis. Cancer Sci. 2011;102:735-41 pubmed publisher
product information
AntibodyID :
44687
AntibodyName :
LS-C44949
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
RBP / Retinol Binding Protein Antibody (C-Terminus) LS-C44949
Specificity :
Recognizes an epitope within the 74-182 C-terminal (CT) sequence (11kD peptide fragment) of human serum Retinol Binding Protein (RBP), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for the transport of Retinol (vitamin A1) from the liver to peripheral target tissues. RBP is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex. An increasing number of studies suggest that the subsequent release of retinol from RBP at the plasma membrane occurs through interaction of RBP with specific membrane receptors.
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
PBS, 0.05% Sodium Azide
ImmunogenDesc :
Human Retinol Binding Protein purified from plasma.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
RBP / Retinol Binding Protein
StandardGeneSymbol :
RBP
Reactivity :
Mouse, Goat, Rat, Rhesus monkey, Human
Usage :
ELISA, IHC, IHC-Fr, IHC-P
ShortWebDescription :
Retinol Binding Protein antibody LS-C44949 is an unconjugated mouse monoclonal antibody to Retinol Binding Protein (RBP ) from human, mouse, rat and other species. Validated for ELISA and IHC. Cited in 1 publication.
UsageText :
Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH6.0 is recommended for this purpose.
Synonyms :
, RBP
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.