This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CD71 / Transferrin Receptor Antibody (clone 8D3, Low Endotoxin) LS-C44905
catalog :
LS-C44905
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
8D3

The same clone is also sold as:
reactivity :
human, mouse
application :
immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
44643
AntibodyName :
LS-C44905
TargetSpecies :
Mouse
Host Species :
Rat
Product Name :
CD71 / Transferrin Receptor Antibody (clone 8D3, Low Endotoxin) LS-C44905
Specificity :
Recognizes mouse CD71, a 95kD cell surface protein that is otherwise known as transferrin receptor. CD71 is a major iron-binding protein, which plays a key role in the transport of iron into cells that require it. In mice, CD71 is widely expressed on a variety of cells, including Sertoli cells and cells which form the blood brain barrier (BBB) in the central nervous system. Recognizes native, soluble and denatured forms of murine CD71. Binding of the 8D3 antibody to CD71 does not inhibit the proliferation of cell lines tested, and does not interfere with the uptake of iron into cells. The antibody has been used as a BBB transporter vector in mice and is suitable for studying CD71 expression, and iron uptake into different tissues, in the mouse.
ClonalityDesc :
Monoclonal
CloneName :
8D3
AntibodyModification :
Low Endotoxin Unconjugated
PresentationDesc :
PBS
ImmunogenDesc :
Mouse transformed endothelioma cell line t. end1.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at -20°C. Avoid freeze-thaw cycles. Store undiluted.
IsotypeName :
IgG2a
Gene :
CD71 / Transferrin Receptor
StandardGeneSymbol :
TFRC
gene family :
Protease
Subfamily :
Metallopeptidase M28B
Reactivity :
Mouse
Usage :
Flo (1:100 - 1:200), IHC, IHC-Fr
ShortWebDescription :
Transferrin Receptor antibody LS-C44905 is an unconjugated rat monoclonal antibody to mouse Transferrin Receptor (CD71). Validated for Flow and IHC.
UsageText :
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 Method sheets are available on request.
Synonyms :
TFRC, CD71, TFR1, TRFR, TFR, TR, CD71 antigen, p90, T9, Transferrin receptor, Transferrin receptor protein 1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.