This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
PDCD1 / CD279 / PD-1 Antibody LS-C44900
catalog :
LS-C44900
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyName :
LS-C44900
TargetSpecies :
Mouse
Host Species :
Rat
Product Name :
PDCD1 / CD279 / PD-1 Antibody LS-C44900
Specificity :
Recognizes mouse CD279, a 55kD cell surface protein which is a member of the CD28/CTLA-4 family, otherwise known as programmed death-1 (PD-1). CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes. Studies suggest that CD279, an immunoinhibitory receptor, plays a critical role in peripheral tolerance induction and prevention of autoimmune disease. Two members of the B7 family, B7-H1 (PD-L1) and B7-DC (PD-L2), have been identified as the ligands for CD279. Antibodies produced by clone RMP1-14 have been reported to block the binding of both B7-H1-Ig and B7-DC-Ig fusion proteins to PD-1 transfected BHK cells(1).
ClonalityDesc :
Monoclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenDesc :
PD-1 transfected BHK cells.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG2a
Gene :
PDCD1 / CD279 / PD-1
StandardGeneSymbol :
PDCD1
gene family :
Apoptosis
Reactivity :
Mouse
Usage :
Flo (1:10 - 1:25), IHC, IHC-Fr
ShortWebDescription :
PD-1 antibody LS-C44900 is an unconjugated rat monoclonal antibody to mouse PD-1 (PDCD1 / CD279). Validated for Flow and IHC.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Synonyms :
PDCD1, CD279, HPD-1, HPD-l, PD1, Protein PD-1, SLEB2, PD-1, CD279 antigen, Programmed cell death 1
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.