This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
NOTCH1 Antibody (clone mN1A, RPE) LS-C44818
catalog :
LS-C44818
clonality :
monoclonal
host :
mouse
conjugate :
RPE
clone name :
mN1A

The same clone is also sold as:
reactivity :
human, mouse
application :
flow cytometry
product information
AntibodyID :
44556
AntibodyName :
LS-C44818
TargetSpecies :
Mouse
Host Species :
Mouse
Product Name :
NOTCH1 Antibody (clone mN1A, RPE) LS-C44818
Specificity :
Specific for mouse Notch1, a single transmembrane receptor which is expressed in a range of cells including hematopoietic cells in mouse fetal liver, adult thymus and bone marrow. Notch1 plays a role in embryonic development and tissue homeostasis in the adult. Recent work has suggested a further role for this receptor in the regulation of lymphopoiesis and myelopoiesis. Following ligand binding, Notch1 is cleaved in the transmembrane domain, releasing the Notch intracellular domain (NICD) to translocate to the nucleus, where it plays a role in the modulation of gene expression.
ClonalityDesc :
Monoclonal
CloneName :
mN1A
AntibodyModification :
RPE
PresentationDesc :
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to cdc10-NCR region within mouse Notch1
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C. Do not freeze. Protect from light.
ResuspensionLiquidDesc :
Reconstitute with distilled water.
IsotypeName :
IgG1
Gene :
NOTCH1
StandardGeneSymbol :
NOTCH1
Reactivity :
Mouse
Usage :
Flo (1:1 - 1:10)
ShortWebDescription :
NOTCH1 antibody LS-C44818 is an RPE-conjugated mouse monoclonal antibody to mouse NOTCH1. Validated for Flow.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Membrane permeabilization is required for this application.
Synonyms :
NOTCH1, Notch 1, TAN1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.