This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
KLRK1 / CD314 / NKG2D Antibody (clone 1D11) LS-C44803
catalog :
LS-C44803
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1D11

The same clone is also sold as:
reactivity :
human
application :
immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
44541
AntibodyName :
LS-C44803
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
KLRK1 / CD314 / NKG2D Antibody (clone 1D11) LS-C44803
Specificity :
Specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding toCD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6).
ClonalityDesc :
Monoclonal
CloneName :
1D11
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Cells
ImmunogenDesc :
NKL cells
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
KLRK1 / CD314 / NKG2D
StandardGeneSymbol :
KLRK1
Reactivity :
Human
Usage :
Flo (1:100), IHC, IHC-Fr, IP
ShortWebDescription :
NKG2D antibody LS-C44803 is an unconjugated mouse monoclonal antibody to human NKG2D (KLRK1 / CD314). Validated for Flow, IHC and IP.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Synonyms :
KLRK1, D12S2489E, CD314 antigen, KLR, NK cell receptor D, NKG2D, NKG2-D, NKG2-D-activating NK receptor, CD314
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.