This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
LAG3 Antibody (clone C9B7W, Low Endotoxin) LS-C44773
catalog :
LS-C44773
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
C9B7W

The same clone is also sold as:
reactivity :
human, mouse
application :
flow cytometry
product information
AntibodyID :
44511
AntibodyName :
LS-C44773
TargetSpecies :
Mouse
Host Species :
Rat
Product Name :
LAG3 Antibody (clone C9B7W, Low Endotoxin) LS-C44773
Specificity :
Recognizes murine lymphocyte activation gene-3 (LAG-3), a 70kD activation-induced cell surface molecule that is also referred to as CD223. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion. Recognizes an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II.
ClonalityDesc :
Monoclonal
CloneName :
C9B7W
AntibodyModification :
Low Endotoxin Unconjugated
PresentationDesc :
PBS
ImmunogenType :
Fusion protein
ImmunogenDesc :
Murine CD223 Ig fusion protein
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
LAG3
StandardGeneSymbol :
LAG3
Reactivity :
Mouse
Usage :
Flo (1:50 - 1:200)
ShortWebDescription :
LAG3 antibody LS-C44773 is an unconjugated rat monoclonal antibody to mouse LAG3. Validated for Flow.
UsageText :
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Synonyms :
LAG3, CD223 antigen, LAG-3, Protein FDC, CD223, FDC, Lymphocyte-activation gene 3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.