This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
NCR1 / NKP46 Antibody (clone AKS1, RPE) LS-C44751
catalog :
LS-C44751
clonality :
monoclonal
host :
mouse
conjugate :
RPE
clone name :
AKS1

The same clone is also sold as:
reactivity :
human, bovine
application :
flow cytometry
product information
AntibodyID :
44489
AntibodyName :
LS-C44751
TargetSpecies :
Bovine
Host Species :
Mouse
Product Name :
NCR1 / NKP46 Antibody (clone AKS1, RPE) LS-C44751
Specificity :
Specific for bovine CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is primarily expressed by a subset natural killer (NK) cells. No expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes. Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells. XXX recommend the use of MCA2365EL for this purpose.
ClonalityDesc :
Monoclonal
CloneName :
AKS1
AntibodyModification :
RPE
PresentationDesc :
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
ImmunogenType :
Fusion protein
ImmunogenDesc :
Fusion protein consisting of the extracellular region of bovine CD335.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
ResuspensionLiquidDesc :
Reconstitute with distilled water.
IsotypeName :
IgG1
Gene :
NCR1 / NKP46
StandardGeneSymbol :
NCR1
gene family :
Immunoglobulin
Reactivity :
Bovine
Usage :
Flo (1:1 - 1:5)
ShortWebDescription :
NKP46 antibody LS-C44751 is an RPE-conjugated mouse monoclonal antibody to bovine NKP46 (NCR1). Validated for Flow.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Synonyms :
NCR1, CD335, HNKp46, NK-p46, Lymphocyte antigen 94 homolog, NK cell-activating receptor, CD335 antigen, LY94, NKP46
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.