This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IL2RB / CD122 Antibody (clone TM-BETA 1, Low Endotoxin) LS-C44744
catalog :
LS-C44744
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
TM-BETA 1

The same clone is also sold as:
reactivity :
human, mouse
application :
immunoprecipitation, flow cytometry
product information
AntibodyID :
44482
AntibodyName :
LS-C44744
TargetSpecies :
Mouse
Host Species :
Rat
Product Name :
IL2RB / CD122 Antibody (clone TM-BETA 1, Low Endotoxin) LS-C44744
Specificity :
Recognizes the murine CD122 cell surface glycoprotein, a 75-85kD molecule also known as interleukin-2 receptor (IL-2R) beta chain. In mouse, CD122 is primarily expressed on natural killer (NK) cells and at lower levels on lymphocyte subsets, monocytes and macrophages. CD122 can associate with the IL-2R alpha chain (CD25) and CD132 to form a functional high affinity receptor complex that binds IL-2. CD132/CD122 heterodimers can also be formed which bind IL-2 with intermediate affinity. IL-2 binding to the IL-2R is important in the generation and differentiation of T lymphocytes and NK cells. Clone TM-beta 1 is reported to block IL-2 high affinity binding to the IL-2R beta receptor. XXX recommend the use of For this purpose.
ClonalityDesc :
Monoclonal
CloneName :
TM-BETA 1
AntibodyModification :
Low Endotoxin Unconjugated
PresentationDesc :
PBS
ImmunogenDesc :
Cells from murine IL-2RB + transformant TART-mBeta.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG2b
Gene :
IL2RB / CD122
StandardGeneSymbol :
IL2RB
gene family :
Interleukin
Reactivity :
Mouse
Usage :
Flo (1:10 - 1:50), IP
ShortWebDescription :
CD122 antibody LS-C44744 is an unconjugated rat monoclonal antibody to mouse CD122 (IL2RB). Validated for Flow and IP.
UsageText :
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Synonyms :
IL2RB, CD122, CD122 antigen, IL-2 receptor subunit beta, IL15RB, Interleukin 15 receptor, beta, p70-75, IL-2R subunit beta, IL-2RB, Interleukin 2 receptor, beta
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.