This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
ITGB3 / Integrin Beta 3 / CD61 Antibody (clone HM beta 3.1, RPE) LS-C44646
catalog :
LS-C44646
clonality :
monoclonal
host :
hamsters
conjugate :
RPE
clone name :
HM beta 3.1

The same clone is also sold as:
reactivity :
human, mouse
application :
flow cytometry
product information
AntibodyID :
44384
AntibodyName :
LS-C44646
TargetSpecies :
Mouse
Host Species :
Hamster
Product Name :
ITGB3 / Integrin Beta 3 / CD61 Antibody (clone HM beta 3.1, RPE) LS-C44646
Specificity :
Recognizes the murine integrin beta 3 subunit (CD61), a 90kD type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrand's factor (vWF), vitronectin and thrombospondin. Clone HM beta 3.1 is reported to partially inhibit the binding of CD61 to fibronectin. XXX recommend the use of MCA2299EL for this purpose.
ClonalityDesc :
Monoclonal
CloneName :
HM beta 3.1
AntibodyModification :
RPE
PresentationDesc :
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
ImmunogenType :
Native protein
ImmunogenDesc :
Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C. Do not freeze. Store untiluted. Protect from light.
ResuspensionLiquidDesc :
Reconstitute with distilled water.
IsotypeName :
IgG
Gene :
ITGB3 / Integrin Beta 3 / CD61
StandardGeneSymbol :
ITGB3
gene family :
Integrin
Reactivity :
Mouse
Usage :
Flo (1:1 - 1:10)
ShortWebDescription :
CD61 antibody LS-C44646 is an RPE-conjugated hamster monoclonal antibody to mouse CD61 (ITGB3 / Integrin Beta 3). Validated for Flow.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Synonyms :
ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.