This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
ITGB3 / Integrin Beta 3 / CD61 Antibody (clone HM beta 3.1, FITC) LS-C44643
catalog :
LS-C44643
clonality :
monoclonal
host :
hamsters
conjugate :
FITC
clone name :
HM beta 3.1

The same clone is also sold as:
reactivity :
human, mouse
application :
flow cytometry
product information
AntibodyID :
44381
AntibodyName :
LS-C44643
TargetSpecies :
Mouse
Host Species :
Hamster
Product Name :
ITGB3 / Integrin Beta 3 / CD61 Antibody (clone HM beta 3.1, FITC) LS-C44643
Specificity :
Recognizes the murine integrin beta 3 subunit (CD61), a 90kD a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrand's factor (vWF), vitronectin and thrombospondin. Clone HM beta 3-1 is reported to partially inhibit the binding of CD61 to fibronectin. XXX recommend the use of MCA2299EL for this purpose.
ClonalityDesc :
Monoclonal
CloneName :
HM beta 3.1
AntibodyModification :
FITC
PresentationDesc :
PBS, 0.09% Sodium Azide, 1% BSA
ImmunogenType :
Native protein
ImmunogenDesc :
Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light.
IsotypeName :
IgG
Gene :
ITGB3 / Integrin Beta 3 / CD61
StandardGeneSymbol :
ITGB3
gene family :
Integrin
Reactivity :
Mouse
Usage :
Flo (1:1 - 1:10)
ShortWebDescription :
CD61 antibody LS-C44643 is an FITC-conjugated hamster monoclonal antibody to mouse CD61 (ITGB3 / Integrin Beta 3). Validated for Flow.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Synonyms :
ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.