This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-CD27L / CD70 Antibody (clone FR70) LS-C44609
catalog :
LS-C44609
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
FR70
reactivity :
human, mouse
application :
immunoprecipitation, flow cytometry
product information
AntibodyID :
44347
AntibodyName :
LS-C44609
TargetSpecies :
Mouse
Host Species :
Rat
Product Name :
Anti-CD27L / CD70 Antibody (clone FR70) LS-C44609
Specificity :
Recognizes mouse CD70, a 30-33kD type II transmembrane protein belonging to the TNF superfamily. CD70 is not expressed on resting T and B lymphocytes but expression is induced on activation. Interaction of CD70 with its ligand CD27 is reported to play an important role in T-cell co-stimulation and the regulation of T-dependant B-cell activation and antibody production. Clone FR70 is reported to block the functions of CD70 and can be used to block the interactions between CD27 and CD70. XXX recommend the use of MCA2302EL for this purpose.
ClonalityDesc :
Monoclonal
CloneName :
FR70
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.4, 0.09% sodium azide.
ImmunogenType :
Cells
ImmunogenDesc :
A20 mouse B cell lymphoma cell line.
PurificationDesc :
Protein G purified
IsotypeName :
IgG2b
Gene :
CD27L / CD70
StandardGeneSymbol :
CD70
gene family :
TNF
Reactivity :
Mouse
Usage :
Flo (1:25 - 1:50), IP
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Synonyms :
CD70, CD27LG, Ki-24 antigen, Surface antigen CD70, CD27 ligand, CD27-L, CD70 antigen, CD70 molecule, TNFSF7
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.