This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
GZMB / Granzyme B Antibody (clone GB11) LS-C44295
catalog :
LS-C44295
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GB11

The same clone is also sold as:
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
44033
AntibodyName :
LS-C44295
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
GZMB / Granzyme B Antibody (clone GB11) LS-C44295
Specificity :
Recognizes the serine protease Granzyme B, which is important in the induction of apoptosis in target cells by cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell, Granzyme B activates the cascade of caspases that finally results in cell death. Has been reported to function as a capture reagent in ELISA assays for soluble Granzyme B in conjunction with biotin conjugated clone GB10 (MCA2119B) as detection reagent.
ClonalityDesc :
Monoclonal
CloneName :
GB11
AntibodyModification :
Unconjugated
PresentationDesc :
TBS, 0.09% Sodium Azide
ImmunogenType :
Purified protein
ImmunogenDesc :
Purified human Granzyme B.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1
Gene :
GZMB / Granzyme B
StandardGeneSymbol :
GZMB
gene family :
Protease
Subfamily :
Serine S1
Reactivity :
Human
Usage :
ELISA (2 - 5 µg/ml), Flo (1:10 - 1:100), IF, IHC, IHC-Fr, IP
ShortWebDescription :
Granzyme B antibody LS-C44295 is an unconjugated mouse monoclonal antibody to human Granzyme B (GZMB). Validated for ELISA, Flow, IF, IHC and IP.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells or 100 ul whole blood. ELISA: This antibody has been reported to function as a capture reagent in sandwich ELISA assays for soluble Granzyme B in conjunction with biotin conjugated clone GB10 (LS-C44294) as detection reagent.
Synonyms :
GZMB, CCPI, CGL-1, Cathepsin G-like 1, CSP-B, CTLA-1, CTLA1, CGL1, CSPB, Fragmentin 2, GRB, HLP, Human lymphocyte protein, Fragmentin-2, SECT, Lymphocyte protease, T-cell serine protease 1-3E, C11, CTSGL1, Cytotoxic serine protease B, Granzyme B, Granzyme-2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.