This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
GZMB / Granzyme B Antibody (clone GB10, Biotin) LS-C44294
catalog :
LS-C44294
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
GB10

The same clone is also sold as:
reactivity :
human
product information
AntibodyID :
44032
AntibodyName :
LS-C44294
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
GZMB / Granzyme B Antibody (clone GB10, Biotin) LS-C44294
Specificity :
Recognizes the serine protease Granzyme B, which is expressed within the granules of cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death. Has been reported to function as a detection reagent in ELISA assays for soluble Granzyme B in conjunction with GB11 (MCA2120) as capture reagent.
ClonalityDesc :
Monoclonal
CloneName :
GB10
AntibodyModification :
Biotin
PresentationDesc :
TBS, 0.001% Thimerosal, 1% BSA
ImmunogenType :
Purified protein
ImmunogenDesc :
Purified human Granzyme B.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
GZMB / Granzyme B
StandardGeneSymbol :
GZMB
gene family :
Protease
Subfamily :
Serine S1
Reactivity :
Human
Usage :
ELISA (1 µg/ml)
ShortWebDescription :
Granzyme B antibody LS-C44294 is a biotin-conjugated mouse monoclonal antibody to human Granzyme B (GZMB). Validated for ELISA.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. ELISA: This antibody has been reported to function as a detection reagent in sandwich ELISA assays for soluble Granzyme B in conjunction with GB11 (LS-C44295) as capture reagent.
Synonyms :
GZMB, CCPI, CGL-1, Cathepsin G-like 1, CSP-B, CTLA-1, CTLA1, CGL1, CSPB, Fragmentin 2, GRB, HLP, Human lymphocyte protein, Fragmentin-2, SECT, Lymphocyte protease, T-cell serine protease 1-3E, C11, CTSGL1, Cytotoxic serine protease B, Granzyme B, Granzyme-2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.