product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
PLAP / Alkaline Phosphatase Antibody (clone H17E2) LS-C44264
catalog :
LS-C44264
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
H17E2
reactivity :
human
application :
ELISA, immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
citations: 4
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Xue L, Li Y, Chen J. Duration of simulated microgravity affects the differentiation of mesenchymal stem cells. Mol Med Rep. 2017;15:3011-3018 pubmed publisher
Gianni T, Salvioli S, Chesnokova L, Hutt Fletcher L, Campadelli Fiume G. ?v?6- and ?v?8-integrins serve as interchangeable receptors for HSV gH/gL to promote endocytosis and activation of membrane fusion. PLoS Pathog. 2013;9:e1003806 pubmed publisher
Gianni T, Leoni V, Chesnokova L, Hutt Fletcher L, Campadelli Fiume G. ?v?3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1. Proc Natl Acad Sci U S A. 2012;109:19792-7 pubmed publisher
Chesnokova L, Hutt Fletcher L. Fusion of Epstein-Barr virus with epithelial cells can be triggered by ?v?5 in addition to ?v?6 and ?v?8, and integrin binding triggers a conformational change in glycoproteins gHgL. J Virol. 2011;85:13214-23 pubmed publisher
product information
AntibodyID :
44002
AntibodyName :
LS-C44264
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PLAP / Alkaline Phosphatase Antibody (clone H17E2) LS-C44264
Specificity :
Recognizes human placental alkaline phosphate, a 67kD isoform expressed in trophoblast cells of normal human placenta, in seminomas and in ovarian carcinoma. The H17E2 antibody has been widely used in immunolocalization studies of germ cell tumors and may also be used in ELISA based assays for the measurement of soluble PLAP.
ClonalityDesc :
Monoclonal
CloneName :
H17E2
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Membrane extract
ImmunogenDesc :
Placental membrane.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
PLAP / Alkaline Phosphatase
StandardGeneSymbol :
ALPP
Reactivity :
Human
Usage :
ELISA, Flo (10 µg/ml), IHC, IHC-Fr
UsageNotRecommended :
IHC-P
ShortWebDescription :
Alkaline Phosphatase antibody LS-C44264 is an unconjugated mouse monoclonal antibody to human Alkaline Phosphatase (PLAP). Validated for ELISA, Flow and IHC. Cited in 4 publications.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul.
Synonyms :
ALPP, ALP, Alkaline phosphomonoesterase, Glycerophosphatase, PALP, PLAP, PLAP-1, Alp1, Germ-cell alkaline phosphatase, Nagao isozyme, Regan isozyme
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.