This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-CD68 Antibody (clone FA-11, FITC) LS-C44119
catalog :
LS-C44119
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
FA-11
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
43857
AntibodyName :
LS-C44119
TargetSpecies :
Mouse
Host Species :
Rat
Product Name :
Anti-CD68 Antibody (clone FA-11, FITC) LS-C44119
Specificity :
Macrosialin is a heavily glycosylated transmembrane protein of 87-115kD, which is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. Macrosialin is the murine homologue of the human macrophage glycoprotein CD68, both are members of the lysosomal-associated membrane protein (LAMP) family which are located predominantly within the cells and can be detected by flow cytometry using cell permeabilization. The antibody does detect surface macrosialin at low levels in resident mouse peritoneal macrophages which can be enhanced with thioglycollate stimulation.
ClonalityDesc :
Monoclonal
CloneName :
FA-11
AntibodyModification :
FITC
PresentationDesc :
PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
ImmunogenType :
Purified protein
ImmunogenDesc :
Purified Concanavalin A acceptor glycoprotein from P815 cell line.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
+4°C or -20°C, Avoid repeated freezing and thawing. Store undiluted.
IsotypeName :
IgG2a
Gene :
CD68
StandardGeneSymbol :
CD68
Reactivity :
Mouse
Usage :
Flo, IF, IHC-Fr, IHC-P, IP, WB
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Synonyms :
CD68, CD68 antigen, gp110, SCARD1, CD68 molecule, LAMP4, Macrophage antigen CD68, Macrosialin
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.