This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
GAP43 Antibody (clone 2G13, Supernatant) LS-C43839
catalog :
LS-C43839
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2G13
reactivity :
human, chicken
application :
immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
43577
AntibodyName :
LS-C43839
TargetSpecies :
Chicken
Host Species :
Mouse
Product Name :
GAP43 Antibody (clone 2G13, Supernatant) LS-C43839
Specificity :
Recognizes a protein originally termed 2G13P which is localized to growth cones. Subsequent investigation has identified this protein to be 40S ribosomal protein SA, also known as 37 kD laminin receptor precursor or Laminin receptor 1. 40S ribosomal protein SA is a 296 amino acid ~37kD membrane, cytoplasmic and nuclear protein required for the assembly and/or stability of the 40S ribosomal subunit. In vertebrate evolution the molecule has acquired a secondary function as a laminin receptor. In growth cones expression is notable particularly in filopodia and lamellipodia in developing rat CNS and embryonic neurons in culture. 40S ribosomal protein SA interacts with the filamentous actin cytoskeleton and therefore may be involved in growth cone motility. Has been used for the detection of growth cones by immunohistochemistry and identification of 40S ribosomal protein SA by western blotting in chicken and rat samples.
ClonalityDesc :
Monoclonal
CloneName :
2G13
AntibodyModification :
Supernatant Unconjugated
PresentationDesc :
0.09% Sodium Azide
ImmunogenType :
Membrane fraction
ImmunogenDesc :
Embryonic chick tectal membranes.
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgM
Gene :
GAP43
StandardGeneSymbol :
GAP43
gene family :
Neuromodulin
Reactivity :
Chicken
Usage :
IHC-Fr, IHC-P
ShortWebDescription :
GAP43 antibody LS-C43839 is an unconjugated mouse monoclonal antibody to chicken GAP43. Validated for IHC.
UsageText :
Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
Synonyms :
GAP43, Axonal membrane protein GAP-43, B-50, Growth associated protein 43, Growth-associated protein 43, Neural phosphoprotein B-50, Neuromodulin, PP46, GAP-43, Protein F1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.