This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
TNF Alpha Antibody (clone MP6-XT22, Low Endotoxin) LS-C43649
catalog :
LS-C43649
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MP6-XT22

The same clone is also sold as:
reactivity :
human, mouse
application :
immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
43387
AntibodyName :
LS-C43649
TargetSpecies :
Mouse
Host Species :
Rat
Product Name :
TNF Alpha Antibody (clone MP6-XT22, Low Endotoxin) LS-C43649
Specificity :
Specific for mouse tumor necrosis factor alpha (TNF alpha), a 17 KDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4+ T cells. TNF alpha forms dimers and trimers, and is also found as a 26KDa integral membrane protein. Mouse TNF alpha has cytolytic activity against many tumor cell lines, and has an important immuno-regulatory role. Clone MP6-XT22 is reported to neutralize the effects of mouse TNF alpha (4,5)
ClonalityDesc :
Monoclonal
CloneName :
MP6-XT22
AntibodyModification :
Low Endotoxin Unconjugated
PresentationDesc :
PBS
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant murine TNF alpha expressed in E. coli.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
TNF Alpha
StandardGeneSymbol :
TNF
gene family :
TNF
Reactivity :
Mouse
Usage :
ELISA (1 - 10 µg/ml), Flo (1:50 - 1:100), IHC, IHC-Fr, IHC-P (10 µg/ml)
ShortWebDescription :
TNF Alpha antibody LS-C43649 is an unconjugated rat monoclonal antibody to mouse TNF Alpha. Validated for ELISA, Flow and IHC.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Membrane permeabilization is required for this application. Method sheets are available on request. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Synonyms :
TNF, APC1 protein, Cachectin, DIF, TNF Alpha, Tumor necrosis factor-alpha, TNF-alpha, TNF-a, TNFA, Tumor necrosis factor, TNF, macrophage-derived, TNF, monocyte-derived, TNFSF2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.