This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IL6ST / CD130 / gp130 Antibody (clone B-T2) LS-C43306
catalog :
LS-C43306
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-T2

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
product information
AntibodyID :
43044
AntibodyName :
LS-C43306
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IL6ST / CD130 / gp130 Antibody (clone B-T2) LS-C43306
Specificity :
Recognizes soluble and membrane bound gp130 receptor, also known as CD130, Interleukin-6 receptor subunit beta, Oncostatin-M receptor subunit alpha or Interleukin-6 signal transducer. CD130 is a 918 amino acid, ~130 kD single pass type-1 transmembrane glycoprotein containing a single and multiple domains. CD130 can be cleaved to form a monomeric soluble ~100 kD form of the receptor detectable in plasma and other biologic fluids where it acts as an IL-6 antagonist. Binds to an epitope dependent at least partially on the presence of the Ig-like domain. Has been reported to block receptor activity and inhibit IL-6 induced proliferation of XG1 cells and IL-27 mediated proliferation of naive CD4+ T cells,.
ClonalityDesc :
Monoclonal
CloneName :
B-T2
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Purified protein
ImmunogenDesc :
Natural soluble gp130 receptor.
PurificationDesc :
Ion exchange chromatography
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
IL6ST / CD130 / gp130
StandardGeneSymbol :
IL6ST
gene family :
Interleukin
Reactivity :
Human
Usage :
ELISA, Flo
ShortWebDescription :
Gp130 antibody LS-C43306 is an unconjugated mouse monoclonal antibody to human gp130 (IL6ST / CD130). Validated for ELISA and Flow.
UsageText :
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Synonyms :
IL6ST, CD130, CD130 antigen, IL-6R subunit beta, IL-6 receptor subunit beta, Membrane glycoprotein gp130, Membrane glycoprotein 130, IL-6RB, CDW130, gp130, IL-6R-beta
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.