This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CD86 Antibody (clone BU63, RPE) LS-C43298
catalog :
LS-C43298
clonality :
monoclonal
host :
mouse
conjugate :
RPE
clone name :
BU63

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
product information
AntibodyID :
43036
AntibodyName :
LS-C43298
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
CD86 Antibody (clone BU63, RPE) LS-C43298
Specificity :
Recognizes human CD86 also known as B7-2, a type I transmembrane protein expressed by monocytes and activated B cells. CD86 acts as a co-stimulatory molecule along with CD80 and is a ligand for CD28 and CTLA-4. CD86 is a member of the Immunoglobulin superfamily and carries an extracellular domain bearing both an domain which contains the CTLA-4 binding site and an adjacent C2-like domain. CD86 plays an important role in co-stimulation of T cell proliferation, IL-2 production and in the primary immune response. Domain depletion epitope mapping studies indicate that the binding site of Mouse anti Human CD86, is located within the Ig-v-like domain of human CD86. Studies suggest that CD86 along with CD80 may be exploited as receptors for adenovirus entry into cells.
ClonalityDesc :
Monoclonal
CloneName :
BU63
AntibodyModification :
RPE
PresentationDesc :
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
ImmunogenType :
Cells
ImmunogenDesc :
Human peripheral blood lymphocytes.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
ResuspensionLiquidDesc :
Reconstitute with distilled water.
IsotypeName :
IgG1
Gene :
CD86
StandardGeneSymbol :
CD86
Reactivity :
Human
Usage :
Flo (1:1 - 1:10)
ShortWebDescription :
CD86 antibody LS-C43298 is an RPE-conjugated mouse monoclonal antibody to human CD86. Validated for Flow.
UsageText :
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Synonyms :
CD86, Activation B7-2 antigen, B7-2, B7.2, B70, CD86 molecule, CTLA-4 counter-receptor B7.2, CD86 antigen, FUN-1, LAB72, BU63, CD28LG2, Ctla-4 counter-receptors b7.2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.