This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IL1RL1 Antibody (N-Terminal) LS-C43164
catalog :
LS-C43164
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
product information
AntibodyID :
42902
AntibodyName :
LS-C43164
TargetSpecies :
Mouse
Host Species :
Rabbit
Product Name :
IL1RL1 Antibody (N-Terminal) LS-C43164
Specificity :
Recognizes an epitope within the N-Terminal region (NT) of mouse ST2, a member of the Toll-interleukin 1 receptor (TIR) superfamily, expressed by mast cells and TH2 helper cells, but not by TH1 effector cells. The majority of TIR superfamily members, which includes the Interleukin-1 receptor (IL-1R1), Toll-like receptors (TLRs) and the cytosolic adaptor proteins MyD88, TIRAP, Trif and TRAM, initiate innate immunity through the ultimate activation of the transcription factor NF-kappaB and are inducers of the inflammatory response. In contrast ST2, which itself is unable to activate NF-kappaB, has been identified as a negative regulator of IL-1R1 and TLR4 signaling by sequestering MyD88 and TIRAP in line with its role as a crucial receptor in TH2-cell mediated responses and.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
N-Terminal
PresentationDesc :
PBS, 0.02% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A 16 AA synthetic peptide located near mouse ST2 N-Terminus. This peptide is common to the three known isoforms of ST2.
PurificationDesc :
Purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
IL1RL1
StandardGeneSymbol :
IL1RL1
Reactivity :
Mouse
Usage :
WB (1 - 2 µg/ml)
ShortWebDescription :
IL1RL1 antibody LS-C43164 is an unconjugated rabbit polyclonal antibody to mouse IL1RL1 (N-Terminal). Validated for WB.
UsageText :
Western Blot: LS-C43164 detects a band of approximately 45kD in mouse kidney cell lysates. (Predicted MW. 62 kD).
Synonyms :
IL1RL1, DER4, Growth stimulation-expressed, IL33R, Interleukin-1 receptor-like 1, Interleukin 1 receptor-like 1, ST2, ST2L, ST2V, FIT-1, Protein ST2, ST2 protein, IL-1R4, IL1R4
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.