This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
GRIA2 / GLUR2 Antibody LS-C43151
catalog :
LS-C43151
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot
product information
AntibodyID :
42889
AntibodyName :
LS-C43151
TargetSpecies :
Rat
Host Species :
Rabbit
Product Name :
GRIA2 / GLUR2 Antibody LS-C43151
Specificity :
Recognizes glutamate receptor subunit 2 (GluR2), a component of the AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid) group of ionotropic glutamate receptors, which play a key role at excitatory synapses, including synaptic transmission, stabilization and plasticity. GluR2 is possibly the most important of the AMPA receptor subunits, responsible for AMPA receptor rectifying properties, control of ion flow and in particular the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2(R) form, containing a critical arginine residue (as opposed to a glutamine residue) in the Transmembrane region 2 (TM2) domain, thereby rendering native AMPA receptors impermeable to calcium.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
10mM HEPES, pH 7.5, 0.09% Sodium Azide, 50% Glycerol, 0.01% BSA
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Keyhole limpet hemocyanin conjugated synthetic peptide corresponding to an amino acid sequence within rat GluR2.
PurificationDesc :
Purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
GRIA2 / GLUR2
StandardGeneSymbol :
GRIA2
gene family :
Ion Channel
Subfamily :
Glutamate receptor - ionotropic (NMDA receptor)
Reactivity :
Rat
Usage :
WB (1:1000)
ShortWebDescription :
GLUR2 antibody LS-C43151 is an unconjugated rabbit polyclonal antibody to rat GLUR2 (GRIA2). Validated for WB.
UsageText :
Western Blot: LS-C43151 detects a band of approximately 100 kD in rat brain hippocampus cell lysates.
Synonyms :
GRIA2, AMPA 2, GluR-K2, Glutamate receptor 2, HBGR2, GluA2, GluR-2, GluR-B, GLUR2, GLURB
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.