This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-CDC25A Antibody LS-C43053
catalog :
LS-C43053
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunoprecipitation
product information
AntibodyID :
42791
AntibodyName :
LS-C43053
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
Anti-CDC25A Antibody LS-C43053
Specificity :
Recognizes Cdc25A (Cell division cycle 25A), a dual specificity protein phosphatase which is involved in the regulation of the cell cycle. Cdc25A is required for progression from G1 to the S phase of the cell cycle, although the protein remains active after the S phase. The activity of Cdc25A is regulated by reversible phosphorylation. Cdc25A is degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. Cdc25A is overexpressed by a wide variety of human cancers. The epitope recognized bymaps to a region between residues 175 and 225 of human Cdc25A using the numbering given in NP_001780.2.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
Tris-citrate/phosphate buffer, 0.1% sodium azide.
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to a region of human CDC25a encoded within exon 9.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
IsotypeName :
IgG
Gene :
CDC25A
StandardGeneSymbol :
CDC25A
gene family :
Protein Phosphatase
Subfamily :
CDC25
Reactivity :
Human
Usage :
IP, WB (1:1000 - 1:10000)
UsageText :
Western Blot: After immunoprecipitation followed by Western blotting, LS-C43053 detects a band of approximately 68 kD in HeLa cell lysates.
Synonyms :
CDC25A, CDC25A2-CAG isoform, Cell division cycle 25A, CDC25A phosphatase, CDC25Hu1, M-phase inducer phosphatase 1, CDC25A2
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.