This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-SMC1A / SMC1 Antibody (phospho-Ser957) LS-C43029
catalog :
LS-C43029
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human
application :
western blot, immunoprecipitation
product information
AntibodyID :
42767
AntibodyName :
LS-C43029
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
Anti-SMC1A / SMC1 Antibody (phospho-Ser957) LS-C43029
Specificity :
Recognizes human structural maintenance of chromosomes-1 (SMC1) which is phosphorylated at Ser957. SMC1 forms a heterodimer with SMC3, and is involved in sister chromatid cohesion and in DNA recombination and repair. SMC1 can be phosphorylated by ATM on serines 957 and 966 in vitro and in vivo in response to ionizing radiation. SMC1 also acts as a downstream effector in the ATM/NBS1 pathway of S-phase checkpoint.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
pSer957
PresentationDesc :
Tris-citrate/phosphate, pH 7.5, 0.09% sodium azide.
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Phosphorylated synthetic peptide corresponding to a region within human SMC1 (locus link ID 5884) around serine 957. ( pSer957 ).
PurificationDesc :
Purified
IsotypeName :
IgG
Gene :
SMC1A / SMC1
StandardGeneSymbol :
SMC1A
Reactivity :
Human
Usage :
IP, WB (1:200 - 1:2000)
UsageText :
Western Blot: LS-C43029 detects a band of approximately 150 kD in Hela cell lysates following treatment with 10 Gy ionizing radiation.
Synonyms :
SMC1A, CDLS2, DXS423E, KIAA0178, SB1.8, SMC protein 1A, SMC1, SMC1L1, SMC-1-alpha, SMC-1A, SMCB
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.