product summary
request information :
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-RAD17
catalog :
LS-C43028
quantity :
price :
clonality :
polyclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human
application :
western blot
more info or order :
LifeSpan Biosciences product webpage
product information
?AntibodyID :
42766
AntibodyName :
LS-C43028
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
Anti-RAD17
Specificity :
Specific for human RAD17 which is phosphorylated at Ser645. RAD17 is a cell cycle checkpoint protein required for activation of checkpoint signaling pathways in response to stalled replication forks and DNA damage. RAD17 is phosphorylated on Ser635 and Ser645 is response to DNA damage and replication inhibitors. Phosphorylation at these residues is also reported in undamaged cycling cells during S and G2/M
ClonalityDesc :
Polyclonal
AntigenModification :
pSer645
PresentationDesc :
Tris-citrate/phosphate, pH 7-8, 0.1% sodium azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Phosphorylated synthetic peptide corresponding to a region within human RAD17 (locus link ID 5884) around serine 645. ( pSer645 ).
PurificationDesc :
Purified
RecommendedStorageDesc :
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
IsotypeName :
IgG
Gene :
RAD17
StandardGeneSymbol :
RAD17
Reactivity :
Human
Usage :
WB (1:500 - 1:5000)
UsageText :
Western Blot: LS-C43028 detects a band of approximately 85-88 kD in Hela cell lysates following treatment with 10 Gy ionizing radiation.
Synonyms :
RAD17, HRAD17, R24L, RAD1 homolog, RAD1 (S. pombe) homolog, RAD24, Rad17-like protein, RF-C activator 1 homolog, CCYC, RAD17 homolog (S. pombe), RAD17SP, RF-C/activator 1 homolog
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.