This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-NBN / Nibrin Antibody LS-C43025
catalog :
LS-C43025
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunoprecipitation
product information
AntibodyID :
42763
AntibodyName :
LS-C43025
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
Anti-NBN / Nibrin Antibody LS-C43025
Specificity :
Recognizes human Nijmegen breakage syndrome 1, also known as nibrin, NBS1 or Cell cycle regulatory protein p95. NBS1 interacts with MRE11 and RAD50 to form a complex with nuclease activity which is involved in the initiation of nonhomologous end joining and homologous recombination. It is thought that NBS1 is involved in both DNA double-strand break repair and DNA damage-induced checkpoint activation. Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by hypersensitivity to ionizing radiation and cancer predisposition.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
Tris-citrate/phosphate, pH 7.5, 0.09% sodium azide.
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to a region within human NBS1 (locus link ID 4683).
PurificationDesc :
Purified
IsotypeName :
IgG
Gene :
NBN / Nibrin
StandardGeneSymbol :
NBN
Reactivity :
Human
Usage :
IP, WB (1:1000 - 1:10000)
Synonyms :
NBN, ATV, AT-V2, Nibrin, NBS1, AT-V1, NBS, p95
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.