product summary
request information :
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-PDGFA / PDGF-A
catalog :
LS-C42997
quantity :
price :
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot, ELISA
more info or order :
LifeSpan Biosciences product webpage
product information
?AntibodyID :
42735
AntibodyName :
LS-C42997
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
Anti-PDGFA / PDGF-A
Specificity :
Specific for human PDGF-AA (Platelet derived growth factor A chain), a disulphide-linked alpha-chain homodimer and member of the PDGF family, released from platelet alpha-granules following trauma/platelet activation. Naturally occurring active forms of PDGF exist as dimers of two alpha chains (AA), two beta chains (BB), or a combination of both chains (AB), all of which signal through the high-affinity PDGF-Ralpha receptor, and the latter two of which can also signal through the PDGF-Rbeta receptor. PDGFs are potent mitogens for a variety of cells including those of the connective tissue, bone and cartilage, blood and smooth muscle cells, and are involved in several biological processes including chemotaxis, hyperplasia and embryonic neurogenesis. An increased expression of PDGF-AA has been associated with a diverse range of conditions including progression of osteosarcomas, persistent Cytomegalovirus infection in kidney allografts and mediation of IL-13-stimulated lung fibroblast proliferation in asthma
ClonalityDesc :
Polyclonal
PresentationDesc :
Lyophilized, PBS, pH 7.4.
ImmunogenDesc :
Recombinant human PDGF-AA.
PurificationDesc :
Purified
ResuspensionLiquidDesc :
Distilled Water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add azide.
IsotypeName :
IgG
Gene :
PDGFA / PDGF-A
StandardGeneSymbol :
PDGFA
gene family :
PDGF
Reactivity :
Human
Usage :
ELISA (0.5 µg/ml), Func (0.17 - 0.19 µg/ml), WB (0.1 - 0.2 µg/ml)
Synonyms :
PDGFA, PDGF-A, PDGF A-chain, PDGF subunit A, PDGF-1, PDGF1
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.