This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
OSM / Oncostatin M Antibody LS-C42995
catalog :
LS-C42995
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA
product information
AntibodyID :
42733
AntibodyName :
LS-C42995
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
OSM / Oncostatin M Antibody LS-C42995
Specificity :
Recognizes human Oncostatin M (OSM), a 209 amino acid pleiotropic cytokine, originally isolated from PMA (phorbol 12-myristate 13-acetate) treated U937 leukaemia cells and mitogen-activated T lymphocytes. OSM was identified by the ability to inhibit the replication of various human tumor cell lines, but has also been shown to exert a stimulatory effect on fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, and to induce the release of certain cytokines by endothelial cells. OSM signals through binding with low affinity to the gp130 protein present in two cell surface receptors: type I consisting of gp130 and LIFR (leucocyte inhibitory factor receptor) which also acts as a receptor for LIF, and type II consisting of gp130 and OSMR, which mediates OSM specific activities.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
Lyophilized PBS, pH 7.4
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human Oncostatin M
PurificationDesc :
Purified
ResuspensionLiquidDesc :
100 µl Distilled Water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add azide.
IsotypeName :
IgG
Gene :
OSM / Oncostatin M
StandardGeneSymbol :
OSM
Reactivity :
Human
Usage :
ELISA (0.5 µg/ml), Func (0.1 - 0.18 µg/ml), WB (0.1 - 0.2 µg/ml)
ShortWebDescription :
Oncostatin M antibody LS-C42995 is an unconjugated rabbit polyclonal antibody to human Oncostatin M (OSM ). Validated for ELISA, Func and WB.
Synonyms :
OSM, Oncostatin-M, Oncostatin M
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.