product summary
request information :
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-MDC / CCL22
catalog :
LS-C42985
quantity :
price :
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot, ELISA
product information
?AntibodyID :
42723
AntibodyName :
LS-C42985
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
Anti-MDC / CCL22
Specificity :
Specific for human MDC (macrophage-derived cytokine), otherwise known as CCL22, a member of the CC chemokine family expressed by macrophages, monocyte-derived dendritic cells, epithelial cells, fibroblasts and highly expressed in the thymus. MDC acts as a chemoattractant for monocytes, dendritic cells, activated T lymphocytes and NK cells, through binding to chemokine (C-C motif) receptor 4 (CCR4). CCR4 is selectively expressed by Th2 cells and several studies have revealed a link between MDC and another ligand of CCR4, known as activation-regulated chemokine (TARC/CCL17), with Th2-mediated inflammatory disorders such as atopic dermatitis
ClonalityDesc :
Polyclonal
PresentationDesc :
Lyophilized, PBS, pH 7.4.
ImmunogenDesc :
Recombinant human MDC.
PurificationDesc :
Purified
ResuspensionLiquidDesc :
Distilled Water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add azide.
IsotypeName :
IgG
Gene :
MDC / CCL22
StandardGeneSymbol :
CCL22
gene family :
Intercrine
Subfamily :
Intercrine beta
Reactivity :
Human
Usage :
ELISA (0.5 µg/ml), Func (5 - 7 µg/ml), WB (0.1 - 0.2 µg/ml)
Synonyms :
CCL22, A-152E5.1, ABCD-1, CC chemokine STCP-1, DC/B-CK, Macrophage-derived chemokine, MDC(1-69), MDC, SCYA22, Small inducible cytokine A22, STCP-1, C-C motif chemokine 22, Small-inducible cytokine A22
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.